瀏覽人氣：805

胡萬炯 醫師

最高學歷：約翰霍普金斯大學國際衛生博士
　　　　　台灣大學醫學士

研究領域：免疫學、腫瘤學、疫苗學

分機：5784

電子信箱：Wanchung.Hu09@tzuchi.com.tw

https://orcid.org/0000-0003-1360-1422

  • 免疫學、腫瘤學、疫苗學
  • 免疫反應架構與致病原和自體免疫研究
  • 癌症幹細胞起因與癌症轉移相關機制研究

參考文獻：

  1. Wanchung Hu, Christian Ockenhouse, Kent Kester, James Cummings, Ann Stewart, Gray Heppner, Anne Jedlicka, Alan Scott, Nathan Wolfe, Maryanne Vahey, and Donald Burke. 2006 Common and Divergent Immune Response Signaling Pathways Discovered in Peripheral Blood Mononuclear Cell Gene Expression Patterns in Pre-symptomatic and Clinically Apparent Malaria Infection and Immunity. 2006,74(10)5561-73 IF3.2 Rank39/93=41% Category: Infectious disease (Hu&Ockenhouse are co-first authors)

  2. Wanchung Hu, Yu-Ting Yen, Sher Singh, Chuan-Liang Kao, and Betty A. Wu-Hsieh SARS-CoV Regulates Immune Function-Related Gene Expression in Human Monocytic Cells. Viral Immunology 2012,25(4)1-12 IF1.69 Rank 135/158=85% Category: Immunology

  3. Wanchung Hu Microarray Analysis of PBMC after Plasmodium falciparum Infection: Molecular Insights into Disease Pathogenesis, Asian Pacific Journal Of Tropical Medicine 2016,9(4):313 IF1.94 Rank 170/363=47% Category: Public, environmental and occupational health

  4. Wanchung Hu Human Immune Responses to Plasmodium falciparum infection: Molecular Evidence for a THαβ and TH17 Bias over Traditional TH1 Immunity, Malaria Journal 2013,12:392 IF2.63 Rank 4/23=17% Category: Tropical medicine

  5. Wanchung Hu A Framework of All Discovered Immunological Pathways and Their Roles for Four Specific Types of Pathogens and Hypersensitivities Frontiers in Immunology 2020,11:article1992 IF5.085 Rank 38/158=24% Category: Immunology

 

 

  • 生物資料庫研究團隊：盧國城教授 、蔡國旺主任。
  1. 1: Shih LJ, Yang CC, Liao MT, Lu KC, Hu WC, Lin CP. An important call:Suggestion of using IL-10 as therapeutic agent for COVID-19 with ARDS and other complications. Virulence. 2023 Dec;14(1):2190650. doi:10.1080/21505594.2023.2190650. PMID: 36914565; PMCID: PMC10026935.
  2.  Yiang GT, Wu YK, Tsai KW, Tzeng IS, Hu WC, Liao MT, Lu KC, Chung HW, Chao YC,Su WL. Immunothrombosis biomarkers as potential predictive factors of acuterespiratory distress syndrome in moderate-to-critical COVID-19: A single-center,retrospective cohort study. Immunol Lett. 2023 Feb;254:30-38. doi:10.1016/j.imlet.2023.01.010. Epub 2023 Jan 23. PMID: 36702261; PMCID:PMC9869627.
  3. Yiang GT, Wu CC, Lu CL, Hu WC, Tsai YJ, Huang YM, Su WL, Lu KC. Endoplasmic Reticulum Stress in Elderly Patients with COVID-19: Potential of Melatonin Treatment. Viruses. 2023 Jan 4;15(1):156. doi: 10.3390/v15010156. PMID: 36680196; PMCID: PMC9863214.
  4. Lee YH, Tsai KW, Lu KC, Shih LJ, Hu WC. Cancer as a Dysfunctional Immune Disorder: Pro-Tumor TH1-like Immune Response and Anti-Tumor THαβ Immune Response Based on the Complete Updated Framework of Host Immunological Pathways. Biomedicines. 2022 Oct 6;10(10):2497. doi: 10.3390/biomedicines10102497. PMID: 36289759; PMCID: PMC9599225.
  5. Liao TH, Wu HC, Liao MT, Hu WC, Tsai KW, Lin CC, Lu KC. The Perspective of Vitamin D on suPAR-Related AKI in COVID-19. Int J Mol Sci. 2022 Sep 14;23(18):10725. doi: 10.3390/ijms231810725. PMID: 36142634; PMCID: PMC9500944. 
  6. Yang CY, Chen YH, Liu PJ, Hu WC, Lu KC, Tsai KW. The emerging role of miRNAs in the pathogenesis of COVID-19: Protective effects of nutraceutical polyphenolic compounds against SARS-CoV-2 infection. Int J Med Sci. 2022 Jul 18;19(8):1340-1356. doi: 10.7150/ijms.76168. PMID: 35928726; PMCID: PMC9346380.
  7. Tsou A, Chen PJ, Tsai KW, Hu WC, Lu KC. THαβ Immunological Pathway as Protective Immune Response against Prion Diseases: An Insight for Prion Infection Therapy. Viruses. 2022 Feb 17;14(2):408. doi: 10.3390/v14020408. PMID: 35216001; PMCID: PMC8877887.
  8. Wen TH, Tsai KW, Wu YJ, Liao MT, Lu KC, Hu WC. The Framework for Human Host Immune Responses to Four Types of Parasitic Infections and Relevant Key JAK/STAT Signaling. Int J Mol Sci. 2021 Dec 10;22(24):13310. doi: 10.3390/ijms222413310. PMID: 34948112; PMCID: PMC8705408.
  9. Liao MT, Wu CC, Wu SV, Lee MC, Hu WC, Tsai KW, Yang CH, Lu CL, Chiu SK, Lu Resveratrol as an Adjunctive Therapy for Excessive Oxidative Stress in Aging COVID-19 Patients. Antioxidants (Basel). 2021 Sep 9;10(9):1440. doi: 10.3390/antiox10091440. PMID: 34573071; PMCID: PMC8471532.
  10. Chiu SK, Tsai KW, Wu CC, Zheng CM, Yang CH, Hu WC, Hou YC, Lu KC, Chao YC. Putative Role of Vitamin D for COVID-19 Vaccination. Int J Mol Sci. 2021 Aug 20;22(16):8988. doi: 10.3390/ijms22168988. PMID: 34445700; PMCID: PMC8396570.
  11. Hu WC. The Central THαβ Immunity Associated Cytokine: IL-10 Has a Strong Anti-Tumor Ability Toward Established Cancer Models <i>In Vivo</i> and Toward Cancer Cells <i>In Vitro</i>. Front Oncol. 2021 Apr 12;11:655554. doi: 10.3389/fonc.2021.655554. PMID: 33912464; PMCID: PMC8072451.
  12. Hu WC. A Framework of All Discovered Immunological Pathways and Their Roles for Four Specific Types of Pathogens and Hypersensitivities. Front Immunol. 2020 Aug 7;11:1992. doi: 10.3389/fimmu.2020.01992. PMID: 32849663; PMCID: PMC7426516.
  13. Hu WC. Microarray analysis of PBMC after Plasmodium falciparum infection: Molecular insights into disease pathogenesis. Asian Pac J Trop Med. 2016 Apr;9(4):313-323. doi: 10.1016/j.apjtm.2016.03.013. Epub 2016 Mar 10. PMID: 27086147.
  14. Chen HJ, Lin YJ, Wu PC, Hsu WH, Hu WC, Wu TN, Chen FP, Lin YL. Study on Yang-Xu Using Body Constitution Questionnaire and Blood Variables in Healthy Volunteers. Evid Based Complement Alternat Med. 2016;2016:9437382. doi: 10.1155/2016/9437382. Epub 2016 May 31. PMID: 27340421; PMCID: PMC4906219.
  15. Hu WC. Human immune responses to Plasmodium falciparum infection: molecular evidence for a suboptimal THαβ and TH17 bias over ideal and effective traditional TH1 immune response. Malar J. 2013 Nov 5;12:392. doi: 10.1186/1475-2875-12-392. PMID: 24188121; PMCID: PMC3928643.
  16. Hu WC, Yen YT, Singh S, Kao CL, Wu-Hsieh BA. SARS-CoV regulates immune function-related gene expression in human monocytic cells. Viral Immunol. 2012 Aug;25(4):277-88. doi: 10.1089/vim.2011.0099. PMID: 22876772; PMCID: PMC3413073.
  17. Ockenhouse CF, Hu WC, Kester KE, Cummings JF, Stewart A, Heppner DG, Jedlicka AE, Scott AL, Wolfe ND, Vahey M, Burke DS. Common and divergent immune response signaling pathways discovered in peripheral blood mononuclear cell gene expression patterns in presymptomatic and clinically apparent malaria. Infect Immun. 2006 Oct;74(10):5561-73. doi: 10.1128/IAI.00408-06. PMID: 16988231; PMCID: PMC1594921.